Valproate µmol/L → µg/mL
Convert valproate from µmol/L to µg/mL
Sources last checked: 2026-11-03
Valproate µmol/L → µg/mL
Convert valproate from µmol/L to µg/mL
Converts units only; reference ranges depend on the laboratory, the assay and the patient.
What is the Valproate µmol/L → µg/mL?
This converter turns a valproate concentration from µmol/L, used by some SI-reporting laboratories and in parts of the literature, into µg/mL (identical to mg/L), the unit most laboratories and dosing references use. It divides by 6.934 (equivalent to multiplying by about 0.1442), derived from the molar mass of valproic acid, 144.21 g/mol.
When to use it
- Reading a valproate level in µmol/L from an SI-reporting letter or study
- Comparing serial levels from laboratories that report in different units
- Using pharmacokinetic references written in mg/L
When not to use it
- Interpreting the value: target ranges depend on the indication (epilepsy, bipolar disorder), the laboratory and the clinical response
- Total levels in hypoalbuminaemia, renal or liver disease, where the free fraction may be substantially higher
How it is calculated
Valproate (µg/mL) = valproate (µmol/L) ÷ 6.934
Clinical pearls and limitations
- Converts units only; reference ranges depend on the laboratory, the assay and the patient.
- Dividing by 6.934 is the same as multiplying by 0.1442; dividing by 7 gives a quick estimate.
- µg/mL and mg/L are numerically identical, so a result in mg/L can be compared directly.
- Free valproate measurement, where available, is more informative than a total level when protein binding is altered.
- Check ammonia in a patient with unexplained drowsiness or confusion on valproate, even if the level is unremarkable.
Frequently asked questions
How do I convert valproate from µmol/L to µg/mL?
Divide by 6.934. For example, 610 µmol/L ÷ 6.934 = 88.0 µg/mL.
What is 1 µmol/L valproate in µg/mL?
1 µmol/L corresponds to 0.144 µg/mL, because 144.21 g/mol × 1 µmol/L = 144.21 µg/L.
When should a valproate level be taken?
For routine monitoring, at steady state and usually as a trough before the next dose; the time of the last dose and the formulation should be documented, because levels fluctuate over the dosing interval.
Evidence and guidelines
Have a follow-up question?
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<p><a href="https://medelix.ai/en/calculators/valproate-umol-l-to-ug-ml">Valproate µmol/L → µg/mL calculator by Medelix</a></p>For healthcare professionals and medical students. These tools support, and do not replace, clinical judgement. Always check results against the original source and your local protocols.