Carbamazepine µg/mL → µmol/L

Convert carbamazepine from µg/mL to µmol/L

Sources last checked: 2026-11-03

Carbamazepine µg/mL → µmol/L

Convert carbamazepine from µg/mL to µmol/L

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Converts units only; reference ranges depend on the laboratory, the assay and the patient.

Source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.Open

What is the Carbamazepine µg/mL → µmol/L?

Carbamazepine levels are reported in µg/mL (identical to mg/L) by most laboratories in Germany, Austria, Turkey and the USA, and in µmol/L by some SI-reporting laboratories. This converter multiplies by 4.232, the factor that follows from the molar mass of carbamazepine (236.27 g/mol). It converts the parent drug only.

When to use it

  • Comparing a carbamazepine level in µg/mL with a source written in µmol/L
  • Documenting therapeutic drug monitoring for a patient moving between laboratories
  • Pharmacokinetic exercises using SI units
  • Exam questions on enzyme-inducing antiepileptic drugs

When not to use it

  • Carbamazepine-10,11-epoxide, the active metabolite, which has a different molar mass and is reported separately when measured
  • Oxcarbazepine or eslicarbazepine, which are monitored as their own metabolite, not as carbamazepine
  • Interpreting a level drawn before steady state or without the time of the last dose

How it is calculated

Carbamazepine (µmol/L) = carbamazepine (µg/mL) × 4.232

Clinical pearls and limitations

  • Converts units only; reference ranges depend on the laboratory, the assay and the patient.
  • 1 µg/mL = 1 mg/L = 4.232 µmol/L; conversely 1 µmol/L = 0.2363 µg/mL.
  • Carbamazepine induces its own metabolism: after starting or increasing the dose, clearance rises over several weeks, so an early level can overestimate later ones.
  • The epoxide metabolite contributes to both effect and toxicity and can accumulate (e.g. with valproate co-medication) without a rise in the parent-drug level; immunoassays differ in how much epoxide they cross-detect.
  • Carbamazepine is a strong inducer of other drugs, and inhibitors such as some macrolides or azoles can raise its level abruptly.

Frequently asked questions

How do I convert carbamazepine from µg/mL to µmol/L?

Multiply by 4.232. For example, 7.3 µg/mL × 4.232 = 31 µmol/L.

Why is the carbamazepine factor 4.232?

Carbamazepine has a molar mass of 236.27 g/mol. 1 µg/mL equals 1 mg/L, and 1000 ÷ 236.27 = 4.232 µmol/L.

Can I use this for carbamazepine epoxide?

No. The epoxide has a different molar mass, so this factor would give a wrong result.

Evidence and guidelines

  1. Primary source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.
  2. PubChem compound summary: carbamazepine (CID 2554), molecular weight 236.27 g/mol.

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