Folate ng/mL → nmol/L

Convert folate from ng/mL to nmol/L

Sources last checked: 2026-11-03

Folate ng/mL → nmol/L

Convert folate from ng/mL to nmol/L

Fill in every field to see the result.

Converts units only; reference ranges depend on the laboratory, the assay and the patient.

Source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.Open

What is the Folate ng/mL → nmol/L?

Serum folate is reported in ng/mL (= µg/L) in Turkey, the USA and many German-speaking laboratories, and in nmol/L in many other European laboratories. This converter multiplies by 2.266, based on the molar mass of folic acid (pteroylmonoglutamic acid, 441.4 g/mol). Natural folates in blood, mainly 5-methyltetrahydrofolate, have a slightly different molar mass, so the factor is a convention used in SI tables.

When to use it

  • Comparing a serum folate in ng/mL with literature that uses nmol/L
  • Following folate status across laboratories with different units
  • Reading research on neural tube defect prevention or anaemia work-up
  • Exam preparation

When not to use it

  • Red-cell folate without checking the report — it is a different specimen with its own reference values, even if the unit looks the same
  • Folic acid doses in mg or µg, which are amounts, not concentrations
  • Judging folate status from a single serum value after a recent meal or supplement

How it is calculated

Folate (nmol/L) = folate (ng/mL) × 2.266

Clinical pearls and limitations

  • Converts units only; reference ranges depend on the laboratory, the assay and the patient.
  • 1 ng/mL = 1 µg/L ≈ 2.266 nmol/L; 6 ng/mL ≈ 13.6 nmol/L.
  • Serum folate reflects recent intake; red-cell folate reflects status over the lifespan of erythrocytes.
  • Haemolysis falsely raises serum folate because red cells contain much more folate than serum.
  • Reference intervals depend on assay and laboratory and differ between serum and red-cell folate.

Frequently asked questions

How do I convert folate from ng/mL to nmol/L?

Multiply by 2.266. For example, 6 ng/mL × 2.266 = 13.6 nmol/L and 12 ng/mL × 2.266 = 27.2 nmol/L.

Where does the factor 2.266 come from?

Folic acid has a molar mass of 441.4 g/mol. 1 ng/mL is 1000 ng/L, and 1000 ÷ 441.4 = 2.266 nmol/L.

Is folate the same as folic acid?

Folate is the umbrella term for the vitamin's forms; folic acid is the synthetic form in supplements. Laboratory assays measure folates in blood and report them against a folic acid–based unit.

Evidence and guidelines

  1. Primary source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.
  2. PubChem compound summary: folic acid (CID 135398658), molecular weight 441.4 g/mol.

Have a follow-up question?

Medelix answers clinical questions from current guidelines and studies — every statement with its source.

Related calculators

Embed this calculatorFree to use on your website, intranet or teaching page. Copy the code below.
<iframe src="https://medelix.ai/en/embed/folate-ngml-to-nmol" title="Folate ng/mL → nmol/L – Medelix" width="100%" height="620" style="border:0;max-width:720px" loading="lazy"></iframe> <p><a href="https://medelix.ai/en/calculators/folate-ng-ml-to-nmol-l">Folate ng/mL → nmol/L calculator by Medelix</a></p>

For healthcare professionals and medical students. These tools support, and do not replace, clinical judgement. Always check results against the original source and your local protocols.