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Torasemide

Torasemid Hexal · ATC code C03CA04

Also known as: Torasemid, Torasémide, Torasemida, Torsemide · Brand names: Torem, Unat, Torasemid Hexal, Sutril Neo, Torventa

Key facts
Active substance
Torasemide
Drug class
Sulfonamide drug
ATC code
C03CA04
Authorisation
authorised nationally; no central EU authorisation
Information as of
2026-11-03

Key facts

Torasemide (US name torsemide) is an oral loop diuretic. Per the US label it is used for oedema due to heart failure, renal disease or hepatic disease, and for hypertension.

What it is used for

  • Oedema associated with heart failure, renal disease or hepatic disease
  • Hypertension, alone or with other antihypertensives

Dosing

  • Heart failure oedema: start 10 mg or 20 mg once daily; titrate by roughly doubling until adequate diuresis (doses above 200 mg not adequately studied)
  • Chronic renal failure oedema: start 20 mg once daily, titrate by doubling (doses above 200 mg not adequately studied)
  • Hepatic cirrhosis oedema: start 5 mg or 10 mg once daily together with an aldosterone antagonist or potassium-sparing diuretic (doses above 40 mg not adequately studied)
  • Hypertension: 5 mg once daily, increase to 10 mg after 4 to 6 weeks if needed; if still insufficient add another antihypertensive
  • Cirrhosis with ascites: diuresis is best initiated in hospital

Contraindications

  • Known hypersensitivity to torasemide or povidone
  • Anuria
  • Hepatic coma

Important warnings

  • Excessive diuresis: dehydration, hypotension and worsening renal function including acute renal failure, especially with salt depletion or RAAS inhibitors
  • Hypokalaemia, hyponatraemia, hypomagnesaemia, hypocalcaemia, hypochloraemic alkalosis; monitor electrolytes
  • Hyperglycaemia and hyperuricaemia (gout rarely precipitated); monitor blood glucose
  • Ototoxicity (tinnitus, usually reversible hearing loss), more likely with high doses, severe renal impairment or hypoproteinaemia
  • In cirrhosis, sudden fluid and electrolyte shifts may precipitate hepatic coma or encephalopathy

Side effects

  • Excessive urination (dose related: 4% at 5 mg and 15% at 10 mg in hypertension trials)
  • Small increases in BUN, creatinine, uric acid, glucose and lipids
  • Postmarketing: pancreatitis, thrombocytopenia, leucopenia, raised transaminases, thiamine deficiency, Stevens-Johnson syndrome/TEN, photosensitivity, acute urinary retention

Interactions

  • NSAIDs: acute renal failure and reduced diuretic/antihypertensive effect; high-dose salicylates: salicylate toxicity
  • CYP2C9 inhibitors (e.g. amiodarone, fluconazole) raise and inducers (e.g. rifampin) lower torasemide levels; torasemide may affect warfarin, phenytoin and celecoxib
  • Lithium: high risk of lithium toxicity; aminoglycosides and ethacrynic acid: increased ototoxicity, avoid aminoglycosides if possible
  • ACE inhibitors/ARBs (hypotension, renal impairment), radiocontrast (renal toxicity), corticosteroids/ACTH (hypokalaemia), cholestyramine (give torasemide at least one hour before or 4 to 6 hours after), probenecid

Pregnancy and breastfeeding

  • No human data on birth defects or miscarriage; no fetotoxicity or teratogenicity in rats and rabbits at the studied doses
  • No data on presence in human milk; diuretics can suppress lactation

Summary of the official product information, written with AI on 2026-11-03. Every number was checked automatically against the original text. Not reviewed by a physician – the full official text is authoritative.

Full official text →

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For patients

Patient information (US)

This product has no separate US patient information.

Authorisation and brand names by country

Medicines with exactly this active-substance composition, as listed in the national registers – alphabetical and without ranking. Whether a product is currently available is not shown here.

Germany

  • Torasemid1 A Pharma Gmbh, Aaa-Pharma Gmbh, Micro Labs Gmbh, Ratiopharm Gmbh, Hexal Ag, Stadapharm Gmbh, Denk Pharma Gmbh & Co. Kg, Abz-Pharma Gmbh, Aliud Pharma Gmbh · 11 register entries
  • ToremBerlin-Chemie Ag · 5 register entries
  • UnatViatris Healthcare Gmbh · 3 register entries

Source: EMA – Article 57 product data (EU/EEA), as of 2026-11-03

Austria

  • Torasemid HexalHexal Pharma Gmbh · 1 register entry

Source: EMA – Article 57 product data (EU/EEA), as of 2026-11-03

Turkey

  • Sutril NeoADEKA İLAÇ SAN. VE TİC. A.Ş. · 4 register entries
  • TorventaWORLD MEDICINE İLAÇ SAN. VE TİC. A.Ş. · 12 register entries

Source: TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, as of 2026-11-03

Brand names in 17 more European countries
Belgium
Torasemide Sandoz, Torrem
Bulgaria
Toraflora, Диурестад, Систонал, Торабрамид, Торазидекс, Торсид, Тригрим, Трифас
Croatia
Diuver, Tomid
Cyprus
Guperul, Tormis
Czechia
Grolan, Torasemid Stada
Estonia
Torasemide, Trifas
Greece
Rosadim, Toresix, Tormis
Hungary
Tretax
Ireland
Torasemide Azure Pharmaceuticals
Italy
Diuremid, Diuresix, Diuretor, Toradiur, Torasemide Hexal, Torasemide Mylan Generics, Torasemide Teva Italia, Torasemide Zentiva
Latvia
Torasemide Hexal, Torasemide Polfarmex, Torasemide Stada, Torasemide Teva, Torasemide Zentiva, Trifas
Lithuania
Torasemide Auxilia, Torasemide Hexal, Torasemide Stada, Torasemide Teva, Torasemide Zentiva, Toridium, Trifas
Luxembourg
Torasemid Micro Labs, Torrem
Poland
Astorid, Diured, Diuver, Ebozan, Toradiur, Toramide, Torsemed, Trifas
Slovenia
Diuver
Spain
Dilutol, Isodiur Hta, Sutril, Torasemida
Sweden
Torasemid Zentiva, Torem

EMA – Article 57 product data (EU/EEA), 2026-11-03

Medelix receives no money from pharmaceutical companies. Brand names are listed alphabetically and without ranking.

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Sources

  1. U.S. Food and Drug Administration. Torsemide (Chartwell RX, LLC) – Prescribing Information, 2025-12-10. DailyMed (NLM), 2026-11-03. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a3d68763-95e0-4ad6-89c2-c4b1c0b43948
  2. EMA – Article 57 product data (EU/EEA), 2026-11-03. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  3. EMA – Article 57 product data (EU/EEA), 2026-11-03. https://www.ema.europa.eu/en/human-regulatory-overview/post-authorisation/data-medicines-iso-idmp-standards-post-authorisation/public-data-article-57-database
  4. TİTCK – Ruhsatlı Beşeri Tıbbi Ürünler Listesi, 2026-11-03. https://www.titck.gov.tr/dinamikmodul/85
  5. Wikidata (CC0): ATC C03CA.

Editorial: Medelix editorial team · last updated 2026-11-03 · How these pages are made · Report an error

Source: U.S. Food and Drug Administration (FDA), prescribing information, via DailyMed (NLM); public domain. Not advertising, not a treatment recommendation. For questions about your own treatment, ask your doctor or pharmacist.