Free T4 (fT4) ng/dL → pmol/L

Convert free t4 (ft4) from ng/dL to pmol/L

Sources last checked: 2026-11-03

Free T4 (fT4) ng/dL → pmol/L

Convert free t4 (ft4) from ng/dL to pmol/L

Fill in every field to see the result.

Converts units only; reference ranges depend on the laboratory, the assay and the patient.

Source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.Open

What is the Free T4 (fT4) ng/dL → pmol/L?

Free thyroxine (fT4) is reported in ng/dL in the USA, Turkey and many German and Austrian laboratories, and in pmol/L in the UK, Scandinavia and most SI-based literature. This converter multiplies by 12.87, the factor in the AMA Manual of Style SI table, which follows from the molar mass of thyroxine (776.87 g/mol). It converts the free hormone only, not total T4.

When to use it

  • Reading a UK, Scandinavian or SI-based guideline or paper that quotes fT4 in pmol/L
  • Comparing a result from a lab that reports ng/dL with an earlier result in pmol/L
  • Documenting thyroid function for a colleague or registry that expects SI units
  • Exam questions and case reports written in SI units

When not to use it

  • Total T4, which is reported in µg/dL or nmol/L and needs a different factor
  • Comparing values from two different immunoassays: the unit conversion is exact, but the methods are not interchangeable
  • Interpreting thyroid status on its own; fT4 is read together with TSH and the clinical picture

How it is calculated

fT4 (pmol/L) = fT4 (ng/dL) × 12.87

Clinical pearls and limitations

  • Converts units only; reference ranges depend on the laboratory, the assay and the patient.
  • 1 ng/dL = 12.87 pmol/L; conversely, 1 pmol/L ≈ 0.078 ng/dL.
  • Report pmol/L to one decimal place; more digits suggest a precision the immunoassay does not have.
  • Reference intervals are method- and laboratory-specific; a converted value must be read against the interval of the lab that measured it.
  • Free hormone immunoassays are susceptible to interference (e.g. biotin supplements, heterophile antibodies); an implausible fT4 is a reason to discuss the sample with the laboratory, not to recalculate.
  • Do not mix up fT4 (ng/dL) with total T4 (µg/dL): the units differ by a factor of 1000 and the analytes are different.

Frequently asked questions

How do I convert free T4 from ng/dL to pmol/L?

Multiply by 12.87. Example: 1.2 ng/dL × 12.87 = 15.4 pmol/L; 2.5 ng/dL × 12.87 = 32.2 pmol/L.

What is 1 ng/dL fT4 in pmol/L?

12.87 pmol/L.

Why is the factor 12.87?

One mole of thyroxine weighs 776.87 g. Converting ng/dL to ng/L (× 10) and dividing by the molar mass gives nmol/L, which × 1000 is pmol/L: 10 000 ÷ 776.87 ≈ 12.87.

Can I compare fT4 from two different labs after converting?

Only roughly. The unit conversion removes the unit difference, but free-hormone assays from different manufacturers give systematically different results, so each value should be judged against its own lab's reference interval.

Evidence and guidelines

  1. Primary source: AMA Manual of Style, 11th ed. (Oxford Academic) — Units of measure converter, Table 2: Selected laboratory tests and conversion factors.
  2. PubChem compound summary: thyroxine (CID 5819), molecular weight 776.87 g/mol.

Have a follow-up question?

Medelix answers clinical questions from current guidelines and studies — every statement with its source.

Related calculators

Embed this calculatorFree to use on your website, intranet or teaching page. Copy the code below.
<iframe src="https://medelix.ai/en/embed/ft4-ngdl-to-pmol" title="Free T4 (fT4) ng/dL → pmol/L – Medelix" width="100%" height="620" style="border:0;max-width:720px" loading="lazy"></iframe> <p><a href="https://medelix.ai/en/calculators/free-t4-ng-dl-to-pmol-l">Free T4 (fT4) ng/dL → pmol/L calculator by Medelix</a></p>

For healthcare professionals and medical students. These tools support, and do not replace, clinical judgement. Always check results against the original source and your local protocols.